There is still a lot of conflicting data around the NGF compounds in lion’s mane.
The two groups of compounds commonly cited are hericenones and erinacines. Hericenones are in the mushroom and erinacines are in the mycelium.
The issue with focusing on hericenones and erinacines is that we know of no reliable lab that can measure these compounds. So regardless of what any product might say in their marketing, there is no way to verify any claims for these compounds.
For erinacines in the mycelium, this is all based on pure mycelium research. Almost all lions mane mycelium products are myceliated grain. This is apples to oranges. Myceliated grain has shown very low levels of the primary actives like beta-glucans so more abstract compounds like erinacines will likely occur in undetectable amounts.
With our Lion’s Mane extract, nothing is removed during the extraction process so even though it is a hot water extract, it will still contain all the non-water-soluble compounds.
Please see this article below that explains more of this in detail: Is Dual Extraction Necessary
Keep in mind these studies use the whole mushroom here:
- Improving effects of the mushroom Yamabushitake
- Reduction of depression and anxiety
- Improvement of cognitive functions
These used un-extracted lions mane mushroom powder. As our product is extracted and still contains the entire mushrooms, it would be consistent with these studies with added bioavailability from being extracted.
Until a reliable lab can measure hericenones and erinacines, we are confident with staying consistent with the existing clinical data.